BDBM652195 (S)-4-(2,2- diphenylacetyl)- 1-(10-oxo- 10,11-dihydro-5H- dibenzo[b,f|azepine- 5-carbonyl) piperazine-2- carboxylic acid::US11905274, Compound C115

SMILES OC(=O)[C@@H]1CN(CCN1C(=O)N1c2ccccc2CC(=O)c2ccccc12)C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=JMCBSEDJUXBHGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652195   

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652195((S)-4-(2,2- diphenylacetyl)- 1-(10-oxo- 10,11-dihy...)
Affinity DataIC50: 38.1nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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