BDBM652178 (S)-4-(bis(2- methoxylphenyl) carbamoyl)-1- (10-oxo-10,11- dihydro-5H-dibenzo [b,f]azepine-5- carbonyl)piperazine- 2-carboxylic acid::US11905274, Compound C94

SMILES COc1ccccc1N(C(=O)N1CCN([C@@H](C1)C(O)=O)C(=O)N1c2ccccc2CC(=O)c2ccccc12)c1ccccc1OC

InChI Key InChIKey=HIHYQLKOQOWYFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652178   

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652178((S)-4-(bis(2- methoxylphenyl) carbamoyl)-1- (10-ox...)
Affinity DataIC50: 10.6nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652178((S)-4-(bis(2- methoxylphenyl) carbamoyl)-1- (10-ox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent