BDBM652168 (S)-4-(2,2- diphenylacetyl)-1-(1- phenylcyclohexanecarbonyl) piperazine-2-carboxylic acid::US11905274, Compound C81

SMILES OC(=O)[C@@H]1CN(CCN1C(=O)C1(CCCCC1)c1ccccc1)C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=PESOQJSBTFZBRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652168   

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652168((S)-4-(2,2- diphenylacetyl)-1-(1- phenylcyclohexan...)
Affinity DataIC50: 22.7nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652168((S)-4-(2,2- diphenylacetyl)-1-(1- phenylcyclohexan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent