BDBM652148 (S)-1-(2,2- diphenylacetyl)- 4-(10H- phenothiazine- 10-carbonyl) piperazine-2- carboxylic acid::US11905274, Compound C12

SMILES OC(=O)[C@@H]1CN(CCN1C(=O)C(c1ccccc1)c1ccccc1)C(=O)N1c2ccccc2Sc2ccccc12

InChI Key InChIKey=AHSDUZNODLFZCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652148   

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652148((S)-1-(2,2- diphenylacetyl)- 4-(10H- phenothiazine...)
Affinity DataIC50: 43.7nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652148((S)-1-(2,2- diphenylacetyl)- 4-(10H- phenothiazine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent