BDBM652143 (S)-1,4-bis(5H- dibenzo[b,f]azepine- 5-carbonyl) piperazine-2- carboxylic acid::US11905274, Compound C3

SMILES OC(=O)[C@@H]1CN(CCN1C(=O)N1c2ccccc2C=Cc2ccccc12)C(=O)N1c2ccccc2C=Cc2ccccc12

InChI Key InChIKey=ZGQISTHCMSMYSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652143   

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652143((S)-1,4-bis(5H- dibenzo[b,f]azepine- 5-carbonyl) p...)
Affinity DataIC50: 32.5nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652143((S)-1,4-bis(5H- dibenzo[b,f]azepine- 5-carbonyl) p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent