BDBM651957 US20240051958, Example 28

SMILES Cc1ccc2oc(nc2c1)C1CCN(CC1)c1cc(=O)n(C)c2cc(O[C@@H]3CCOC3)c(nc12)C#N

InChI Key InChIKey=JZCQMKQXJPJTCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651957   

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM651957(US20240051958, Example 28)
Affinity DataIC50: 0.140nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent