BDBM651933 US20240051958, Example 4

SMILES Cc1ccc2oc(nc2c1)C1CCN(CC1)c1nc(=O)n(C)c2ccc(Cl)cc12

InChI Key InChIKey=HCTMZPRMNRRGOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651933   

TargetDiacylglycerol kinase alpha(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM651933(US20240051958, Example 4)
Affinity DataIC50: 4.43nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent