BDBM651855 US20240051956, Example 7

SMILES COC1CCN(CC1)n1cc2c(N[C@H](C)c3cccc(C(F)F)c3F)nc(C)nc2cc1=O

InChI Key InChIKey=JNTPUKVXRLEKMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651855   

TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049](Human)
Qilu Regor Therapeutics

US Patent
LigandPNGBDBM651855(US20240051956, Example 7)
Affinity DataIC50: 15nMAssay Description:This assay is used to examine the potency with which compounds inhibit the protein protein interaction between SOS1 and KRAS G12D in a defined bioche...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent