BDBM651837 6-chloro-3-(1H-pyrazol-4-yl)- 2-(5-(trifluoromethyl)-4H- 1,2,4-triazol-3-yl)-1H-pyrrolo- [3,2-b]pyridin-5-ol::US20240051954, Example 49

SMILES Oc1nc2c(-c3cn[nH]c3)c([nH]c2cc1Cl)-c1nnc([nH]1)C(F)(F)F

InChI Key InChIKey=MZFMNJAEZYPVLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651837   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651837(US20240051954, Example 49 | 6-chloro-3-(1H-pyrazol...)
Affinity DataIC50: 294nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent