BDBM651835 6-chloro-5-methoxy-3-(1H- pyrazol-4-yl)-2-(5-(trifluoro- methyl)-4H-1,2,4-triazol-3-yl)- 1H-pyrrolo[3,2-b]pyridine::US20240051954, Example 47

SMILES COc1nc2c(-c3cn[nH]c3)c([nH]c2cc1Cl)-c1nnc([nH]1)C(F)(F)F

InChI Key InChIKey=QUQHBWRRHNFHCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651835   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651835(US20240051954, Example 47 | 6-chloro-5-methoxy-3-(...)
Affinity DataIC50: 91nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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