BDBM651831 5-(6-chloro-5-methoxy-1-meth- yl-3-(1H-pyrazol-4-yl)-1H- pyrrolo[3,2-b]pyridin-2-yl)- N,N-dimethyl-4H-1,2,4- triazole-3-carboxamide::US20240051954, Example 43

SMILES COc1nc2c(-c3cn[nH]c3)c(-c3nnc([nH]3)C(=O)N(C)C)n(C)c2cc1Cl

InChI Key InChIKey=AEKTXGAMGYUAHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651831   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651831(US20240051954, Example 43 | 5-(6-chloro-5-methoxy-...)
Affinity DataIC50: 98nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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