BDBM651830 1-(5-(6-chloro-5-methoxy-1- methyl-3-(1H-pyrazol-4-yl)- 1H-pyrrolo[3,2-b]pyridin-2- yl)-4H-1,2,4-triazol-3-yl)ethan- 1-one::US20240051954, Example 42

SMILES COc1nc2c(-c3cn[nH]c3)c(-c3nnc([nH]3)C(C)=O)n(C)c2cc1Cl

InChI Key InChIKey=RJCWJWLROIGDDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651830   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651830(US20240051954, Example 42 | 1-(5-(6-chloro-5-metho...)
Affinity DataIC50: 66nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent