BDBM651826 1-(5-(6-chloro-3-(1H-imidazol- 1-yl)-5-methoxy-1-methyl-1H- pyrrolo[3,2-b]pyridin-2-yl)- 4H-1,2,4-triazol-3-yl)-N,N- dimethylethan-1-amine::US20240051954, Example 38

SMILES COc1nc2c(c(-c3nnc([nH]3)C(C)N(C)C)n(C)c2cc1Cl)-n1ccnc1

InChI Key InChIKey=RVGWXBZTHPWQTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651826   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651826(US20240051954, Example 38 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 335nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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