BDBM651824 1-(5-(6-chloro-3-(1H-imidazol- 1-yl)-5-methoxy-1-methyl- 1H-pyrrolo[3,2-b]pyridin-2-yl)- 4H-1,2,4-triazol-3-yl)-2-meth- oxy-N,N-dimethylethan-1-amine::US20240051954, Example 36

SMILES COCC(N(C)C)c1nnc([nH]1)-c1c(-n2ccnc2)c2nc(OC)c(Cl)cc2n1C

InChI Key InChIKey=MWPARRJTVPHFFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651824   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651824(US20240051954, Example 36 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 454nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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