BDBM651816 1-(5-(6-chloro-3-(1H-imidazol- 1-yl)-5-methoxy-1-methyl-1H- pyrrolo[3,2-b]pyridin-2-yl)-4H- 1,2,4-triazol-3-yl)-2,2,2- trifluoroethan-1-ol::US20240051954, Example 28

SMILES COc1nc2c(c(-c3nnc([nH]3)C(O)C(F)(F)F)n(C)c2cc1Cl)-n1ccnc1

InChI Key InChIKey=JQJWTOGXIOWLJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651816   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651816(US20240051954, Example 28 | 1-(5-(6-chloro-3-(1H-i...)
Affinity DataIC50: 61nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent