BDBM651812 2-(1-(5-(6-chloro-3-(1H- imidazol-1-yl)-5-methoxy-1- methyl-1H-pyrrolo[3,2-b]- pyridin-2-yl)-4H-1,2,4-triazol- 3-yl)-2,2,2-trifluoroethoxy)- ethan-1-ol::US20240051954, Example 24

SMILES COc1nc2c(c(-c3nnc([nH]3)C(OCCO)C(F)(F)F)n(C)c2cc1Cl)-n1ccnc1

InChI Key InChIKey=DDKDQYWSWUXZOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651812   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651812(US20240051954, Example 24 | 2-(1-(5-(6-chloro-3-(1...)
Affinity DataIC50: 114nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent