BDBM651808 5-(6-chloro-3-(1H-imidazol-1- yl)-5-methoxy-1-methyl-1H- pyrrolo[3,2-b]pyridin-2-yl)-N- methyl-4H-1,2,4-triazol-3- amine::US20240051954, Example 20

SMILES CNc1nnc([nH]1)-c1c(-n2ccnc2)c2nc(OC)c(Cl)cc2n1C

InChI Key InChIKey=ONFXRXVUTHMXPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651808   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651808(US20240051954, Example 20 | 5-(6-chloro-3-(1H-imid...)
Affinity DataIC50: 824nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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