BDBM651796 6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,2,4- triazol-3-yl)-5-methoxy-1- methyl-3-(1H-pyrazol-4-yl)- 1H-pyrrolo[3,2-b]pyridine::US20240051954, Example 8

SMILES COCC(F)(F)c1nnc([nH]1)-c1c(-c2cn[nH]c2)c2nc(OC)c(Cl)cc2n1C

InChI Key InChIKey=PINMCERGZMOXMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651796   

TargetCyclic GMP-AMP synthase [147-522](Human)
Novartis

US Patent
LigandPNGBDBM651796(US20240051954, Example 8 | 6-chloro-2-(5-(1,1-difl...)
Affinity DataIC50: 55nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following: 50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitrog...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
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