BDBM651732 1-(2-methoxyethyl)-2- ((5-(trifluoromethoxy)- 1H-benzo[d]imidazol-2- yl)amino)-1H-benzo[d]- imidazole-5-carboxylic acid::US20240051952, Example 75

SMILES COCCn1c(Nc2nc3ccc(OC(F)(F)F)cc3[nH]2)nc2ccccc12

InChI Key InChIKey=VOPFIKGHKFHZHD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651732   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651732(US20240051952, Example 75 | 1-(2-methoxyethyl)-2- ...)
Affinity DataEC50:  370nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent