BDBM651706 N-(1,3-dihydroxy- propan-2-yl)-1-methyl- 2-((6-(trifluorometh- oxy)benzo[d]oxazol-2- yl)amino)-1H-benzo- [d]imidazole-5-carbox- amide::US20240051952, Example 48

SMILES Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3o2)nc2cc(ccc12)C(=O)NC(CO)CO

InChI Key InChIKey=GVKQMHNRUSNBSR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651706   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651706(US20240051952, Example 48 | N-(1,3-dihydroxy- prop...)
Affinity DataEC50:  2.00E+3nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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