BDBM651700 N-(2-(2-hydroxy-2- methylpropoxy)ethyl)- 1-methyl-2-((6-(tri- fluoromethyl)benzo[d]- oxazol-2-yl)amino)-1H- benzo[d]imidazole-5- carboxamide::US20240051952, Example 42

SMILES Cn1c(Nc2nc3ccc(cc3o2)C(F)(F)F)nc2cc(ccc12)C(=O)NCCOCC(C)(C)O

InChI Key InChIKey=JAAFVYZLTCEQEK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651700   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651700(US20240051952, Example 42 | N-(2-(2-hydroxy-2- met...)
Affinity DataEC50:  2.30E+3nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent