BDBM651685 2-(benzo[d]oxazol-2-yl- amino)-N-(2-hydroxy- propyl)-1-methyl-1H- benzo[d]imidazole-5- carboxamide::US20240051952, Example 23

SMILES CC(O)CNC(=O)c1ccc2n(C)c(Nc3nc4ccccc4o3)nc2c1

InChI Key InChIKey=PUFCOHCGHSOGAR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651685   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651685(US20240051952, Example 23 | 2-(benzo[d]oxazol-2-yl...)
Affinity DataEC50:  2.10E+3nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
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