BDBM651657 US20240051936, Compound 70

SMILES COc1c2C(=O)N(Cc2ccc1COC(=O)Nc1ccc(C)c(Cl)c1)C1CCC(=O)NC1=O

InChI Key InChIKey=ZGFHPHUKNIQMOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651657   

TargetProtein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandPNGBDBM651657(US20240051936, Compound 70)
Affinity DataIC50: 1.90E+3nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1-[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent