BDBM651653 US20240051936, Compound 59

SMILES COc1cc(COC(=O)Nc2cnc(c(C)c2)-c2ccccc2)cc2C(=O)N(Cc12)C1CCC(=O)NC1=O

InChI Key InChIKey=CJPOCWXKYPARLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651653   

TargetProtein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandPNGBDBM651653(US20240051936, Compound 59)
Affinity DataIC50: 600nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1-[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent