BDBM651621 US20240051936, Compound 27

SMILES Cc1cc(Cl)cc(NC(=O)OCc2cc3C(=O)N(Cc3c(F)c2)C2CCC(=O)NC2=O)c1

InChI Key InChIKey=DMTNLYHIMRKHRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651621   

TargetProtein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandPNGBDBM651621(US20240051936, Compound 27)
Affinity DataIC50: 1.55E+3nMAssay Description:Compound activity was monitored in a fluorescence polarization (FP) homogeneous assay using 1-[5-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent