BDBM651530 Preparation of 1-(prop-2-ynyl)-N-(tetrahydro-2H-pyran-2-yloxy)-4-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)piperidine-4-carboxamide ::US20240050571, Compound 9

SMILES FC(F)(F)Oc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCN(CC#C)CC2)C(=O)NOC2CCCCO2)cc1

InChI Key InChIKey=RYBRMTJFTKIDHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 651530   

TargetInterstitial collagenase(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM651530(US20240050571, Compound 9 | Preparation of 1-(prop...)
Affinity DataIC50: 860nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

Target72 kDa type IV collagenase(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM651530(US20240050571, Compound 9 | Preparation of 1-(prop...)
Affinity DataIC50: 0.240nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
Loyola University Of Chicago

US Patent
LigandPNGBDBM651530(US20240050571, Compound 9 | Preparation of 1-(prop...)
Affinity DataIC50: 0.300nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent