BDBM651501 (R)-55-Bromo-10-methyl-14H-6-oxa-3-aza-2(2,6),5(3,2)-dipyridina-1(3,4)-triazolacyclodecaphan-4-one::US11897898, Example 2

SMILES C[C@@H]1CCCOc2ncc(Br)cc2C(=O)Nc2cccc(n2)-c2nncn12

InChI Key InChIKey=CYQZVMZXSRYCNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651501   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651501(US11897898, Example 2 | (R)-55-Bromo-10-methyl-14H...)
Affinity DataIC50: 5.50E+3nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
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