BDBM651497 US11897898, Example 46

SMILES C[C@H]1CCCOc2ncc(cc2C(=O)Nc2cccc(n2)-c2nncn12)C1CN(C1)C(=O)OC(C)(C)C

InChI Key InChIKey=HNRFCSWZEKBSJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651497   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651497(US11897898, Example 46)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent