BDBM651493 US11897898, Example 40

SMILES COC(C)(C)c1cnc2OCCC[C@H](C)n3cnnc3-c3cccc(NC(=O)c2c1)n3

InChI Key InChIKey=DVUGQKUABYOGMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651493   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651493(US11897898, Example 40)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent