BDBM651475 US11897898, Example 11

SMILES C[C@H]1CN(C[C@@H](C)N1)c1cnc2OCCC[C@H](C)n3cnnc3-c3cccc(NC(=O)c2c1)n3

InChI Key InChIKey=LAAXGBJYTZJEFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651475   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen Ma

US Patent
LigandPNGBDBM651475(US11897898, Example 11)
Affinity DataIC50: 100nMAssay Description:The protein kinase inhibitory activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Corp. (Malvern, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
Go to US Patent