BDBM651387 (E)-2-(5-((4-(2-hydroxyethyl)piperidin-1-yl)sulfonyl)-2-propoxyphenyl)-5-methyl-4-oxo-7-propyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carbaldehyde oxime::US11897890, Compound lr

SMILES CCCOc1ccc(cc1-c1nn2c(CCC)c(\C=N\O)c(C)c2c(=O)[nH]1)S(=O)(=O)N1CCC(CCO)CC1

InChI Key InChIKey=QFKPKUQLHDKHDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651387   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM651387((E)-2-(5-((4-(2-hydroxyethyl)piperidin-1-yl)sulfon...)
Affinity DataIC50: 0.160nMAssay Description:Experimental protocol: The test compound, i.e the compound of the present invention, reference compound or water (control) are added to a buffer cont...More data for this Ligand-Target Pair
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Date in BDB:
4/18/2024
Entry Details
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