BDBM651382 US11897876, Example 15::[(3S)-3-(3,5-Difluorophenyl)isoxazolidin-2-yl]-[1-[5-fluoro-6-(2-methylpyrazol-3-yl)pyrimidin-4-yl]-4-piperidyl]methanone

SMILES Cn1nccc1-c1ncnc(N2CCC(CC2)C(=O)N[C@@H](CCO)c2cc(F)cc(F)c2)c1F

InChI Key InChIKey=HALUTUAANBWFIK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651382   

TargetReceptor-interacting serine/threonine-protein kinase 1 [1-375](Human)
Genzyme

US Patent

LigandBDBM651382([(3S)-3-(3,5-Difluorophenyl)isoxazolidin-2-yl]-[1-...)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:In detail, 2 μl recombinantly produced hRIPK1 (aa 1-375) fusion protein (end concentration 3.6 μg/ml) and 2 μl compound (end concentra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
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