BDBM651367 3-Fluoro-5-[(3S)-2-[1-[6-(5-methyl-1,3,4-oxadiazol-2-yl)pyrimidin-4-yl]piperidine-4-carbonyl]isoxazolidin-3-yl]benzonitrile::Substituted Phenyl-Isoxazolidin of Comparator Example C::US11897876, Comparator Example E

SMILES Cc1nnc(o1)-c1cc(ncn1)N1CCC(CC1)C(=O)N1OCC[C@H]1c1cc(F)cc(c1)C#N

InChI Key InChIKey=AQRRNELJHIFIEG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651367   

TargetReceptor-interacting serine/threonine-protein kinase 1 [1-375](Human)
Genzyme

US Patent

LigandBDBM651367(Substituted Phenyl-Isoxazolidin of Comparator Exam...)Copy SMILESCopy InChI

Affinity DataIC50: 35nMAssay Description:In detail, 2 μl recombinantly produced hRIPK1 (aa 1-375) fusion protein (end concentration 3.6 μg/ml) and 2 μl compound (end concentra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
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