BDBM651111 US20240043470, Compound 1-64

SMILES CN1[C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cccc(Oc3cccc(C[C@H](N4CCCC4=O)C1=O)c3)c2)C(=O)NCC(F)(F)F

InChI Key InChIKey=JCVPXBZLPUGMFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651111   

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651111(US20240043470, Compound 1-64)
Affinity DataIC50: 2.72E+3nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651111(US20240043470, Compound 1-64)
Affinity DataIC50: 1.00E+5nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent