BDBM650964 US20240043442, Example 46A::US20240043442, Example 46B

SMILES CC1Cc2c([nH]c3ccc(F)cc23)C(N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key InChIKey=ABNJPIFXICOEIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650964   

TargetEstrogen receptor(Human)
Inventisbio

US Patent
LigandPNGBDBM650964(US20240043442, Example 46A | US20240043442, Exampl...)
Affinity DataIC50: 0.400nMAssay Description:Compound activity was analyzed using celltiter-glo luminescent viability assay (Promega #G7572) in breast cancer cell line MCF-7. Cells grown in log ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetEstrogen receptor(Human)
Inventisbio

US Patent
LigandPNGBDBM650964(US20240043442, Example 46A | US20240043442, Exampl...)
Affinity DataIC50: 100nMAssay Description:Compound activity was analyzed using celltiter-glo luminescent viability assay (Promega #G7572) in breast cancer cell line MCF-7. Cells grown in log ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent