BDBM650959 US20240043442, Example 42A::US20240043442, Example 42B

SMILES CC1Cc2c([nH]c3ccc(Cl)cc23)C(N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key InChIKey=HNNHEZMFTUVYOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650959   

TargetEstrogen receptor(Human)
Inventisbio

US Patent
LigandPNGBDBM650959(US20240043442, Example 42A | US20240043442, Exampl...)
Affinity DataIC50: 1.90nMAssay Description:Compound activity was analyzed using celltiter-glo luminescent viability assay (Promega #G7572) in breast cancer cell line MCF-7. Cells grown in log ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetEstrogen receptor(Human)
Inventisbio

US Patent
LigandPNGBDBM650959(US20240043442, Example 42A | US20240043442, Exampl...)
Affinity DataIC50: 100nMAssay Description:Compound activity was analyzed using celltiter-glo luminescent viability assay (Promega #G7572) in breast cancer cell line MCF-7. Cells grown in log ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent