BDBM650796 US20240043440, Example 12::US20240043440, Example 13::US20240043440, Example 14

SMILES Cc1ncc(-c2cc(nc3sc(c(N)c23)S(=O)C2CCCCC2)-c2nccs2)n1C

InChI Key InChIKey=ZQDDDNVKXOWYRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 650796   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650796(US20240043440, Example 12 | US20240043440, Example...)
Affinity DataIC50: 2.60nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650796(US20240043440, Example 12 | US20240043440, Example...)
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM650796(US20240043440, Example 12 | US20240043440, Example...)
Affinity DataIC50: 186nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent