BDBM650764 (2R,3S)-2-(4-(cyclopentyl(thieno[2,3-c]pyridin-7- yl)amino)phenyl)-N-(4-methyl-3- (trifluoromethyl)phenyl)piperidine-3-carboxamide::US20240043439, Compound 173

SMILES Cc1ccc(NC(=O)[C@H]2CCCN[C@H]2c2ccc(cc2)N(C2CCCC2)c2nccc3ccsc23)cc1C(F)(F)F

InChI Key InChIKey=WEJJVJKDUICGLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650764   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandChemical structure of BindingDB Monomer ID 650764BDBM650764((2R,3S)-2-(4-(cyclopentyl(thieno[2,3-c]pyridin-7- ...)
Affinity DataIC50: 1.00E+5nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent