BDBM650754 US20240043439, Compound 205::cis-1-(2-fluoro-6-methylbenzoyl)-N-(1-methyl-1H- indazol-5-yl)-2-(4-(((R)-2-(trifluoromethyl)pyrrolidin-1- yl)methyl)phenyl)octahydro-1H-cyclopenta[b]pyridine-3- carboxamide

SMILES Cc1cccc(F)c1C(=O)N1[C@H]2CCC[C@H]2CC(C1c1ccc(CN2CCC[C@@H]2C(F)(F)F)cc1)C(=O)Nc1ccc2n(C)ncc2c1

InChI Key InChIKey=XTMWRFWKFNKXBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650754   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650754(cis-1-(2-fluoro-6-methylbenzoyl)-N-(1-methyl-1H- i...)
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
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