BDBM650746 US20240043439, Compound 202::tert-butyl 6-cis-2-(4-(cyclopentylamino)phenyl)-1-(2- fluoro-6-methylbenzoyl)octahydro-1H- cyclopenta[b]pyridine-3-carboxamido)-3,4- dihydroisoquinoline-2(1H)-carboxylate

SMILES Cc1cccc(F)c1C(=O)N1C2CCCC2CC(C1c1ccc(NC2CCCC2)cc1)C(=O)NC1N(CCc2ccccc12)C(=O)OC(C)(C)C

InChI Key InChIKey=GAQQBPPNPQPHBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650746   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650746(tert-butyl 6-cis-2-(4-(cyclopentylamino)phenyl)-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650746(tert-butyl 6-cis-2-(4-(cyclopentylamino)phenyl)-1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent