BDBM650745 US20240043439, Compound 201::cis-2-(4-(cyclopentyl(methyl)amino)phenyl)-1-(2-fluoro- 6-methylbenzoyl)-N-(2-methyl-1,2,3,4- tetrahydroisoquinolin-6-yl)octahydro-1H- cyclopenta[b]pyridine-3-carboxamide

SMILES CN(C1CCCC1)c1ccc(cc1)C1C(C[C@@H]2CCC[C@@H]2N1C(=O)c1c(C)cccc1F)C(=O)Nc1ccc2CN(C)CCc2c1

InChI Key InChIKey=LJHPRWUDIBZUTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650745   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650745(cis-2-(4-(cyclopentyl(methyl)amino)phenyl)-1-(2-fl...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650745(cis-2-(4-(cyclopentyl(methyl)amino)phenyl)-1-(2-fl...)
Affinity DataIC50: 1.00E+5nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent