BDBM650744 (2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl-3- (trifluoromethyl)phenyl)piperidine-3-carboxamide::US20240043439, Compound 200

SMILES Cc1ccc(NC(=O)[C@H]2CCCN[C@H]2c2ccc(NC3CCCC3)cc2)cc1C(F)(F)F

InChI Key InChIKey=JBOYAEOGXSIDJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650744   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650744((2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650744((2R,3S)-2-(4-(cyclopentylamino)phenyl)-N-(4-methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent