BDBM650727 (2R,3S,4aR,7aS)-2-(4-(cyclopentylamino)phenyl)-1-(2- fluoro-6-methylbenzoyl)-N-(1-methyl-1H-indol-5- yl)octahydrofuro[3,4-b]pyridine-3-carboxamide::US20240043439, Compound 139
SMILES Cc1cccc(F)c1C(=O)N1[C@@H]2COC[C@@H]2C[C@@H]([C@@H]1c1ccc(NC2CCCC2)cc1)C(=O)Nc1ccc2n(C)ccc2c1
InChI Key InChIKey=XHJPQFYWQNXXBG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 650727
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.75E+4nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair