BDBM650693 (2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)-N-(1H-indazol-5-yl)octahydro-1H-cyclopenta[b]pyridine-3-carboxamide::US20240043439, Compound 84

SMILES Cc1cccc(F)c1C(=O)N1[C@@H]2CCC[C@@H]2C[C@@H]([C@@H]1c1ccc(NC2CCCC2)cc1)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=LKQIYJQVHLEPGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650693   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650693((2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-1-(...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2024
Entry Details
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