BDBM650689 US20240043439, Compound 77::cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- methylbenzoyl)-N-(2-methyl-1,2,3,4- tetrahydroisoquinolin-6-yl)octahydro-1H- cyclopenta[b]pyridine-3-carboxamide
SMILES CN1CCc2cc(NC(=O)C3C[C@@H]4CCC[C@@H]4N(C3c3ccc(NC4CCCC4)cc3)C(=O)c3c(C)cccc3F)ccc2C1
InChI Key InChIKey=YDLMOWJYRGKSPG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 650689
Affinity DataIC50: 1.00E+5nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair