BDBM650677 US20240043439, Compound 63::cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- methylbenzoyl)-N-(6-methylpyridin-3-yl)octahydro-1H- cyclopenta[b]pyridine-3-carboxamide

SMILES Cc1ccc(NC(=O)C2C[C@@H]3CCC[C@@H]3N(C2c2ccc(NC3CCCC3)cc2)C(=O)c2c(C)cccc2F)cn1

InChI Key InChIKey=VAIYCJCHSYWARV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 650677   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650677(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Kira Pharmaceuticals (Suzhou)

US Patent
LigandPNGBDBM650677(cis-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6- ...)
Affinity DataIC50: 7.50E+4nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent