BDBM650666 (2R,3S,4aR,7aR)-2-(4-(cyclopentylamino)phenyl)-N-(4- (dimethylamino)phenyl)-1-(2-fluoro-6- methylbenzoyl)octahydro-1H-cyclopenta[b]pyridine-3- carboxamide::US20240043439, Compound 51
SMILES CN(C)c1ccc(NC(=O)[C@H]2C[C@H]3CCC[C@H]3N([C@H]2c2ccc(NC3CCCC3)cc2)C(=O)c2c(C)cccc2F)cc1
InChI Key InChIKey=XJHIGXUYSKPIPP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 650666
Affinity DataIC50: 2.55E+3nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair