BDBM650661 (3S,4R)-4-(4-(cyclopentylamino)phenyl)-N-(4-methyl-3- (trifluoromethyl)phenyl)-6-oxo-1,2,3,4,6,11,12,12a- octahydrobenzo[e]pyrido[1,2-a]azepine-3-carboxamide::US20240043439, Compound 44
SMILES Cc1ccc(NC(=O)[C@H]2CCC3CCc4ccccc4C(=O)N3[C@H]2c2ccc(NC3CCCC3)cc2)cc1C(F)(F)F
InChI Key InChIKey=KMLCMFYZXQDYMY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 650661
Affinity DataIC50: 2.75E+4nMAssay Description:U937 cells were originally obtained from the American Type Culture Collection (ATCC) and transfected with human C5a receptor (C5aR). U937/C5aR cells ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+3nMAssay Description:Migration assay was performed by using polycarbonate membrane with 3.0 m pore (Corning). U937/C5aR cells were collected and washed twice by PBS; cell...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:U937/C5aR cells or HEK293/C5aR cells were washed by PBS and suspended in growth media at the density of 1 106 cells/ml. Seed 2 cell suspension to the...More data for this Ligand-Target Pair