BDBM649762 8-fluoro-4-hydroxy-3-methyl- 6-(3-(4-(pyrrolidin-1- yl)phenyl)-1,2,4-thiadiazol-5- yl)-3,4-dihydro-2H- benzo[e][1,3]oxazin-2-one::US20240043395, Compound 178

SMILES CN1C(O)c2cc(cc(F)c2OC1=O)-c1nc(ns1)-c1ccc(cc1)N1CCCC1

InChI Key InChIKey=LSKZVQUIYSBHHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649762   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649762(8-fluoro-4-hydroxy-3-methyl- 6-(3-(4-(pyrrolidin-1...)
Affinity DataIC50: 1.20E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649762(8-fluoro-4-hydroxy-3-methyl- 6-(3-(4-(pyrrolidin-1...)
Affinity DataIC50: 430nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent