BDBM649753 5-(3-(4-(3,3-difluoroazetidin- 1-yl)phenyl)-1,2,4-thiadiazol- 5-yl)-3-fluoro-2- hydroxybenzaldehyde::US20240043395, Compound 169

SMILES Oc1c(F)cc(cc1C=O)-c1nc(ns1)-c1ccc(cc1)N1CC(F)(F)C1

InChI Key InChIKey=QFYXKDYKPXQMIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649753   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649753(5-(3-(4-(3,3-difluoroazetidin- 1-yl)phenyl)-1,2,4-...)
Affinity DataIC50: 2.50E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649753(5-(3-(4-(3,3-difluoroazetidin- 1-yl)phenyl)-1,2,4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent